Oryx and Crake by Margaret Atwood

Set in the near future this story examines the hideous consequences faced by mankind in a world where genetic engineering has run rampant. Though frequently grotesque and very dark there is a steady stream of humour that runs throughout the book, which means that although it is large its easy to read. It is a highly topical read and many of the fictional abominations created by the scientists in the book are now being talked of on the Internet as if they really exist. Who knows......